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Scientific Reports 5 (2015) 14516

Rapid low dose electron tomography using a direct electron detection camera

by Vadim Migunov, Henning Ryll, Xiaodong Zhuge, Martin Simson, Lothar Strüder, K Joost Batenburg, Lothar Houben, and Rafal E Dunin-Borkowski

Scientists from the Ernst Ruska-Centre used a transmission electron microscope to record almost 3500 images in 3.5 seconds for the reconstruction of a 3D electron tomogram. Previously, 10 to 60 minutes and a ten-fold greater electron dose were required to record such image sequences. The new capability is particularly suitable for examining biological cells, bacteria and viruses, whose structure can be damaged by the electron beam. In addition, it enables dynamic processes, such as chemical reactions and electronic switching phenomena, to be visualized in real time in three dimensions with sub-nanometre precision. The findings have been published in the journal Scientific Reports.

Further reading:

Vadim Migunov, Henning Ryll, Xiaodong Zhuge, Martin Simson, Lothar Strüder, K Joost Batenburg, Lothar Houben, and Rafal E Dunin-Borkowski: Rapid low dose electron tomography using a direct electron detection camer
a, Scientific Reports 5 (2015) 14516.

Jülich Research Centre Press Release of 5 October 2015.

   
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